W0280

Maturation Effects on the Chemical and Crystallographic Changes in the Mammalian Teeth Enamel. Joseph D. Ferrara1, Felicitas B. Bidlack2 and Przemyslaw Dera3, 1Rigaku/MSC, Inc, 9009 New Trails Dr., The Woodlands, TX 77381, 2Dept. of Anthropology, The George Washington Univ., G St NW, Washington DC 20052., 3Geophysical Laboratory, Carnegie Institution of Washington, 5251 Broad Branch Rd. NW, Washington, DC 20015.

Dental development begins in humans and many other mammals in utero, and can extend for years after birth. Tooth enamel, dentin, and cementum are variations of mineralized organic-matrix structures. Carbonato-apatite ((Ca5(PO4)3(OH)x), the major mineral component of tooth enamel (~96 wt %), is largely responsible for the mechanical properties of the tooth. The initial enamel mineralization and subsequent maturation occur through a series of complex interactions between proteins and ions. These processes, resulting in a highly organized and complicated arrangements of enamel prisms, are not well understood. Although in histology the incremental nature of tooth formation is well visible, it is not clear whether and how it correlates with the pattern of enamel maturation. A better understanding of this relationship is vital for a wide array of analyses, where modern or fossil enamel is sampled to obtain information about an organisms diet. Previously published crystallographic studies of tooth enamel were performed with ground samples. We studied thin sections of equid teeth by means of powder X-ray diffraction. The use of a Rigaku R-AXIS RAPID diffractometer enabled us to obtain high-quality diffraction data, allowing Rietveld refinement of the structure of enamel apatite as a function of the location of the sampling point. It has been suggested that the chemical changes accompanying tooth maturation include mainly incorporation of hydroxyl and carbonate anions, as well as substitution of Ca, by Na, Sr and Ba. Full Rietveld refinements, involving modeling of substitutional disorder, have allowed the determination of these variations. The movement of matrix secreting cells during the initial phase of crown formation results in distinct spatial arrangement of enamel prisms. We found that the size, shape and orientational preferences in the distribution of apatite crystal change with enamel maturation. Pole-figure analysis of our diffraction data revealed clear trends in these properties.