13.06: Structural Genomics - Big and Small

Oral Presentations

Honolulu/Kahuka

Monday, July 24



01:30 - 02:00 PM 13.06.01
(W0316) 		Ian Wilson.
The Joint Center For Structural Genomics: A Multitiered Approach To Structural Genomics.

02:00 - 02:20 PM 13.06.02
(W0384) 		Min Zhou.
Expression, Purification and Crystallization Methods Developed at the MCSG Adoptable to a Structural Biology Laboratory.
et al: Youngchang Kim, Pearl Quartey, Hui Li, Ruying Wu, Cathy Hatzos, Lour Volkart, Grazyna Joachimiak, Mark Donnelly, Andrzej Joachimiak.

02:20 - 02:40 PM 13.06.03
(W0589) 		Joseph Luft.
High Throughput Optimization of Initial Crystallization Conditions.
et al: Stacey Gulde, Angela Lauricella, Meriem Said, Jennifer Smith, Max Thayer, Christina Veatch, Jennifer Wolfley, Michael Malkowski, George DeTitta.

02:40 - 03:00 PM 13.06.04
(W0024) 		Chunmin Li.
Biological Crystallization Resource: Facilitating Knowledge- Based Biological Macromolecule Crystallization.
et al: Kevin Kirkwood, Brayer Gary.

03:00 - 03:30 PM
Coffee Break.

03:30 - 04:00 PM 13.06.05
(W0503) 		Olga Kirillova.
Structural Genomics Experimental Pipelines - Insights from the First Five Years.
et al: Marek Grabowski, Heping Zheng, Zbyszek Otwinowski, Wladek Minor.

04:00 - 04:20 PM 13.06.06
(W0309) 		Minmin Yu.
Probability- based Cryo Condition Optimization Procedure for High- throughput X-ray Crystallography.
et al: Evan Bursey, Thirumuruhan Radhakannan, Li-Wei Hung.

04:20 - 04:40 PM 13.06.07
(E0006) 		Bernhard Rupp.
Robotic Crystal Harvesting: The Final Frontier in Automated High Throughput Crystallography.
et al: Peter Carmen, Jace Walsh, Echo Miller, Robert Viola.

04:40 - 05:00 PM 13.06.08
(W0606) 		Jason McCoy.
The Role of Follow-Up Studies at the Center for Eukaryotic Structural Genomics.
et al: Abolfazl Arabshahi, Eduard Bitto, Craig Bingman, Frank Ruzicka, Perry Frey, George Phillips.

Poster Presentations

Hawaii Ballroom

Sunday, July 23


S-P051
(W0648) 		Phasing and Modeling of Large Structures with Se-SAD - Crystal Structure of Deblocking Aminopeptidase.
ANDRZEJ JOACHIMIAK, CHANGSOO CHANG, RUIYING WU, JAMES ABDULLAH, MARCIN CYMBOROWSKI, WLADEK MINOR.

M-P052
(E0040) 		The 40 Residues that Control Folding, Cofactor Binding, Catalysis, Oligomerizatio and Function of 13000 Short Chain Oxidoreductase Enzymes.
W.L. Duax, R. Huether, V. Pletnev, C.M. Weeks, T. Umland, Q. Mao, L. Gambino.

M-P054
(E0045) 		A Structural Genomics Analysis of Histidine Kinase Sensor Domains.
J. Cheung, W.A. Hendrickson.

M-P056
(W0184) 		In situ Extension as a Protocol for Identifying Novel Alpha-Amylase Inhibitors.
Gary Brayer, Chunmin Li, Anjuman Begum, Stephen Withers.

M-P058
(W0197) 		An Automated Image Collection System for Crystallization Experiments using SBS Standard Microplates.
Erik Brostromer, Jie Nan, Xiao-Dong Su.

M-P060
(W0199) 		A Laboratory Information Management System for High Throughput Laboratory Environment.
Jie Nan, Xiao-Dong Su.

M-P062
(W0315) 		The Joint Center for Structural Genomics: A Multi-tiered approach to structural genomics.
Marc Elsliger, A. Deacon, A. Godzik, S. A. Lesley, K. O. Hodgson, J. Wooley, K. Wuthrich, I. A. Wilson.

M-P064
(W0365) 		Improved Success Rate Of Molecular Replacement.
Lukasz Jaroszewski, Robert Schwarzenbacher, Adam Godzik.

M-P066
(W0378) 		Generation of Expression Clones Using High- Throughput Technologies for Protein Structure Determination and Drug Discovery.
Shiu Moy, YoungChang Kim, Changsoo Chang, Jerzy Osipiuk, Rongguang Zhang, Hui Li, Ruiying Wu, Frank Collart, Andrzej Joachimiak.

M-P068
(W0397) 		Structure of B. subtlis NrdI - an Auxiliary Protein of Class Ib Ribonucleotide Reductase has Flavodoxin Fold and Binds FMN.
Ruiying Wu, RongGuang Zhang, Shiu F. Moy, Andrzej Joachimiak.

M-P070
(W0452) 		Structure of Toprim Domain- containing Protein from Bacillus stearothermophilus.
Pavlina Rezacova, Dominika Borek, Shiu Moy, Andrzej Joachimiak, Zbyszek Otwinowski.

M-P072
(W0456) 		CrystalMation: Capacity, Reproducibility and Efficiency of a Fully Integrated Automatic High- Throughput Crystallization Platform.
Jian Xu, David Robbins, Rollan Mosko, Matt Lundy, Tom Vorndran, Mandel Mickley, Michael Willis.

M-P074
(W0459) 		Structural Iinvestigations of the Hydrophobic Core of the FAD Dependent Thymidylate Synthase.
Irimpan Mathews, Heath Klock, Eileen Ambing, Scott Lesley, Ashley Deacon.

M-P076
(W0506) 		Structural and Biochemical Studies of the Tryptophan 2,3- dioxygenase Reveal the Molecular Detail of Tryptophan Oxidation.
Farhad Forouhar, Ross Anderson, Chris Mowat, Sergey M. Vorobiev, Mariam Abashidze, Seetharaman Jayaraman, Chiara Bruckmann, Gaetano T. Montelione, Steve Chapman, Liang Tong.

M-P078
(W0552) 		Optimization of Protein Crystallization Screens at the Ontario Centre for Structural Proteomics.
Tatiana Skarina, Elena Evdokimova, Linda Xu, Alexander Ignatchenko, Aled Edwards, Alexei Savchenko.

M-P080
(W0553) 		Identification of Small Molecule Ligands for Structural Genomics Targets and their Application in Crystallization Trials.
Elena Evdokimova, Tatiana Skarina, Marina Kudritska, Linda Xu, Olga Egorova, Micha Pennycoock-Brown, Alexanfra Ezersky, Aled Edwards, Alexandre Yakunin, Alexei Savchenko.

M-P082
(W0554) 		The Undiscovered Bourne: The Helsinki Low-volume Medium- throughput Crystallisation Facility.
Adrian Goldman, Pirkko Heikinheimo, Seija Mäki, Veli-Pekka Jaakola, Lari Lehtiö, Heidi Repo.

M-P084
(W0562) 		A Nearly- Automated High- Throughput Method for Identifying Well-Expressed Soluble Protein Variants.
Evan Bursey, Thomas Terwilliger, Li-Wei Hung.

T-P182
(E0066) 		Automated Analysis Of Vapor Diffusion Crystallization Drops With An X-ray Beam On Beamline FIP-BM30A At The ESRF.
J.-L. Ferrer L. Jacquamet J. Joly M. Pirocchi P. Charrault J. Ohana A. Bertoni L. Apostol R. Kahn F. Borel

S-P187
(W0614) 		Crystal Structure of the Ternary Complex of Allantoate- amidohydrolase with its Substrate and a Ligand: A Crucial Enzyme of Purine Catabolism from E. coli K12.
Rakhi Agarwal, Subramanyam Swaminathan.

T-P200
(E0064) 		Gleaning Functions From Structures Of Treponemal Lipoproteins.
Chad A Brautigam, Ranjit K. Deka, Diana R. Tomchick, Mischa Machius, Lori Neil, Michael V. Norgard.

S-P225
(W0660) 		An Automated Postdoctoral Robot Approach to Small-scale Structural Genomics.
Nicholas Larsen, Andrew Murray, Christopher Walsh, Stephen Harrison.

Contact: aca-inquiries@hwi.buffalo.edu

Last updated: Tue Jul 25 17:48:21 2006

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