ACA Spring 1998 Newsletter

Table of Contents

President's Column

Roster - ACA

Roster - U.S. National Committee

Nominations for Patterson Award

Awards

Ewald Prize Nomination

Daniel Appleman 1931-1998

Coordinate Holds and the PDB

ACA Meeting Moves to Crystal City

Workshops and Schools

ACA Corporate Members

ACA Summer School

Polycrystal Book Service

Calendar of Meetings

Contributors to this issue

Employment Information

Contributions to the ACA Newsletter should be sent to either of the Co-Editors:
Ron Stenkamp
Dept. of Biol. Structure
Box 357420
U. of Washington
Seattle, WA 98195-7420
tel. 206-685-1721
fax 206-543-1524
stenkamp@u.washington.edu

Judith L. Flippen-Anderson
Code 6030
Naval Research Labatory
Washington, DC 20375
tel. 202-767-3463
fax 202-767-6874
flippen@harker.nrl.navy.mil

Articles by e-mail are especially welcome. Deadlines for newsletter contributions are: February 1, May 1, August 1, and November 1. Matters pertaining to advertisements, membership inquiries, or use of the ACA mailing list should be addressed to:

Marcia J. Colquhoun, Administrative Manager
American Crystallographic Association
c/o Hauptman-Woodward Medical Research Institute
73 High Street
Buffalo, NY 14203-0096
tel. 716-856-9600, ext. 321; fax 716-852-4846
E-mail: marcia@hwi.buffalo.edu

ACA Home Page http://www.hwi.buffalo.edu/ACA/

ACA Newsletter (ISSN 1058-9945) Number 1, 1998. Published four times per year in the spring, summer, fall and winter for the membership of the American Crystallographic Association, P.O. Box 96, Ellicott Station, Buffalo, NY 14205-0096. Membership in the ACA includes a non-deductible charge of $1.75 from membership dues to be applied to a subscription to the ACA Newsletter. PERIODICALS POSTAGE PAID AT BUFFALO, NY. POSTMASTER: Send address changes to ACA, c/o 73 High St., Buffalo, NY, 14203.

President's Column
This promises to be an interesting year for the ACA and I am honored to serve as President this year. With the arrival of 1998, Carol Huber completed her three years on Council. Carol provided exceptional service to the organization over the period and through some substantial changes in her life. We wish her good health and know that she maintains a keen interest in the organization. Jon Clardy will continue to serve the ACA as Past-President and as representative to the US National Committee on Crystallography. I look forward to enjoying Jon's wise counsel for another year. Council is pleased to welcome Abe Clearfield as Vice-President; Abe expands the technical expertise of the Council and I look forward to his leadership.
We are all indebted to the people in Buffalo, including Marcia Colquhoun, Patti Coley, Sally Lunge, and Bill Duax. They all contribute a great deal to the organization, as do our newsletter editors, Ron Stenkamp and Judy Flippen-Anderson. The success of the ACA depends on the contributions of many excellent volunteers like these. I hope each of you will find an opportunity to contribute to the organization.
If the rest of 1998 measures up to the events of January, this could be quite a year. As you will learn elsewhere in the newsletter, we had to move the site of our July meeting at very short notice. The Meetings Committee, Judy Flippen-Anderson, S.N. Rao, and Marcia Colquhoun, in consultation with the local organizers, acted very quickly to move the meeting to the Hyatt Regency Crystal City conveniently located near the Washington National Airport. The date of the meeting remains the same, July 18 - 23 and we hope to see you there. Program Chair, Louis Delbaere, and the Special Interest Groups have planned a full program of scientific sessions covering the range of interests in the ACA, including a Transaction Symposium on Crystal Engineering and the Fankuchen Memorial Award lecture. A special symposium will be held at the meeting to honor the 50th anniversary of the IUCr; it is organized by Henk Schenk and the IUCr Executive and will be presented at each Regional Affiliate meeting this year. Council hopes to award a second Elizabeth Wood Science Writing Award at the Washington, D.C. meeting.
Please contact any member of Council with your suggestions and concerns. We hope to provide the service and meetings you need.
Penny Codding

Roster - ACA - 1998
OFFICERS

PRESIDENT
Penelope Codding
Vice-Pres. Acad. & Provost
University Of Victoria
PO Box 1700
Victoria BC V8W 2Y2
CANADA
tel. 250-721-7010
fax 250-721-7216
pcodding@uvic.ca

VICE PRESIDENT
Abraham Clearfield
Dept. of Chemistry

Texas A & M University
P.O. Box 300012
College Station, TX 77842
tel. 409-845-2936
fax 409-845-2370
clearf@acxrd.chem.tamu.edu

PAST PRESIDENT
Jon Clardy
Dept. of Chemistry
Baker Lab
Cornell University
Ithaca, NY 14853-1301
tel. 607-255-7583
fax 607-255-1253
jcc12@cornell.edu

TREASURER
Jane F. Griffin
Dept. of Molec. Biophysics
Hauptman-Woodward Med. Res. Inst.
73 High St.
Buffalo, NY 14203-1196
tel. 716-856-9600 ext. 363
fax 716-852-4846
griffin@hwi.buffalo.edu

SECRETARY
Virginia Pett
Department of Chemistry
The College of Wooster
Wooster, OH 44691
tel. 330-263-2114
fax 330-263-2386
pett@acs.wooster.edu

CANADIAN REP
George Ferguson
Dept. of Chemistry
University of Guelph
Guelph ONT N1G 2W1
CANADA
tel. 519-824-4120 ext. 3548
Fax 519-766-1499
ferguson@chembio.uoguelph.ca

APPOINTMENTS
IUCr REP
Philip Coppens
Dept. of Chemistry
SUNY, Buffalo
732 Nat. Sci. & Math Complex
Buffalo, NY 14260-3000
tel. 716-645-6800 *2217
fax 716-645-6963
CHE9990@UBVMS

FINANCIAL ADVISOR
S.N. Rao
Admin. Bldg. Room 218
Box 0175
University of Central Oklahoma
100 North University Dr.
Edmond, OK 73034-0175
tel. 405-341-2980 ext. 2524
fax 405-330-3830
snrao@aix1.ucok.edu

EXECUTIVE OFFICER
William L. Duax
Hauptman-Woodward Med. Res. Inst.
73 High St.
Buffalo, NY 14203-1196
tel. 716-856-9600 ext 308
fax 716-852-4846
duax@hwi.buffalo.edu

ADMINISTRATIVE MANAGER
Marcia Colquhoun
ACA
P.O. 96 Ellicott Station
Buffalo, NY 14205-0096
tel. 716-856-9600 ext 321
fax 716-852-4846
marcia@hwi.buffalo.edu

NEWSLETTER EDITORS
Judith Flippen-Anderson
Code 6030
Naval Research Laboratorie
Washington, DC 20375
tel. 202-767-3463
fax 202-767-6874
flippen@harker.nrl.navy.mil

Ronald Stenkamp
Box 357420
Dept. of Biological Structure
Seattle, WA 98195-7420
tel. 206-685-1721
fax 206-543-1524
stenkamp@u.washington.edu

CANADIAN DIVISION OFFICERS
Lynn Howell, Chair
Dept. of Biochemistry
Hosp. For Sick Children
555 University Ave.
Toronto, ONT M5B 1X8
tel. 416-597-5933
fax 416-813-5022
howell@sickkids.on.ca

James F. Britten, Secretary
Dept. of Chemistry
McMaster University
1280 Main St. West
Hamilton, ONT ABB-417
tel. 905-525-9140 ext. 23481
fax 905-522-2509
xman@xraysg.chemistry. mcmaster.ca

ACA SPECIAL INTEREST GROUPS

AMORPHOUS MATERIALS
John Kieffer, Chair
Dept. of Matl. Sci. & Eng.
U. of Illinois-Urbana Champaign
1304 W. Green St., MC-246
Urbana, IL 61801
tel. 217-244-4364
fax 217-244-6917
johnk@uiuc.edu

Ronald Cappelletti, Chair elect
Dept. of Physics
Ohio University
Athens, OH 45701
fax 614-593-0433
cappltti@helios.phy.ohiou.edu

Woitek Dmowski, Sec/Treas.
Dept. of Matl. Sci. & Eng.
U. of Pennsylvania
3231 Walnut St. LRSM
Philadelphia, PA 19104
tel. 215-898-9045
dmowski@pdfvax.1rsm.upenn.edu

BIOLOGICAL MACROMOLECULES
Judith Kelly, Chair
Dept. of Mol. & Cell Bio.
Univ. of Connecticut
75 N Eagleville Rd Box U125
Storrs CT 06269-3125
tel. 860-486-4353
fax 860-486-4331
kelly@uconnvm.uconn.edu

William Stallings, Chair-elect
Monsanto BB4k
700 Chesterfield Village Pkwy
Chesterfield, MO 63198
tel. 314-537-7236
fax 314-537-7425
wcstal@ccmail.monsanto.com

Kathryn Ely, Sec./Treas.
Dept. of Structural Biology
Burnham Institute
10901 N. Torrey Pines Rd.
LaJolla, CA 92037-1062
tel. 619-455-6480 ext 591
fax 619-455-0249
ely@ljcrf.edu

FIBER DIFFRACTION
Wade Adams, Chair
425 Dayton Towers #12F
Dayton OH 45410-1161
tel. 513-255-6652
fax 513-255-1128
adamsww@ml.wpafb.af.mil

Greg Beaucage, Chair-elect
Materials Science & Eng.
Univ. of Cincinnati
498 Rhodes Hall ML12
Cincinnati, OH 45221-0172
tel. 513-556-3063
gbeaucage@uceng.uc.edu

Gerald Stubbs, Sec/Treas.
Dept. of Mol. Bio.
Vanderbilt Univ.
Box 1820 Station B
Nashville, TN 37235-1820
tel. 615-322-2018
stubbsgj@ctrvax.vanderbilt.edu

GENERAL INTEREST
Carolyn Brock, Chair
Dept. of Chem.
U. of Kentucky
Lexington, KY 40506-0055
tel. 606-257-1959
fax 606-323-1069
cpbrock@ukcc.uky.edu

Bryan Craven, Chair-elect (NEW ADDRESS)
Dept. of Chemistry
Indiana Univ.of Penn
Indiana, PA 15705
412 357 5784
craven@vms.cis.pitt.edu

Robert Blessing, Sec/Treas.
Hauptman-Woodward MRI
73 High St.
Buffalo, NY 14203
tel. 716-856-9600 ext 335
fax 716-852-6086
blessing@hwi.buffalo.edu

Margaret Kastner, Member-at-Large
Dept. of Chem.
Bucknell U.
Lewisburg, PA 17837
tel. 717-524-1452
fax 717-524-1739
kastner@bucknell.edu

MATERIALS SCIENCE
Jim Kaduk, Chair
Amoco Res Ctr.-Amoco Corp.
PO Box 3011
Naperville IL 60566-7011
tel. 708-420-4547
fax 708-420-5252
kaduk@amoco.com

David E Cox, Chair-elect
Physics Department 510B
Brookhaven National Lab
Upton, NY 11973-5000
tel. 516-344-3818
fax 516-344-2739
cox@bnlx7a.nsls.bnl.gov

Dick Harlow, Sec/Treas.
7 Shull Dr. Devon
Newark DE 19711
tel. 302-695-2097
fax 302-695-1351
harlow@esvax.dnet.dupont.com

Douglas A. Keszler, Member- at-Large
Dept. of Chemistry
Oregon State University
Corvallis OR 97331
tel. 503-754-6736
fax 503-737-2072
keszlerd@ccmail.orst.edu

NEUTRON SCATTERING
Robert Von Dreele, Chair
Los Alamos Natl. Lab.
Los Alamos, NM 87545
tel. 505-667-3630
fax 505-665-2656
vondreele@lanl.gov

Raymond G Teller, Chair-elect
BP America Inc.
4440 Warrensville Center Rd
Cleveland, OH 44128-2837

tel. 216-586-5953
fax 216-586-5621
tellerg@chqp01.usachem.msnet.bp.com

J. Richardson, Sec/Treas.
IPNS Div.
Argonne National Lab
9700 S. Cass Ave.
Argonne, IL 60439
richardson@anlpns.anl.gov

SERVICE CRYSTALLOGRAPHY
Philip Fanwick, Chair
Dept. of Chem.
Purdue University
W. Lafayette, IN 47907-1393
tel. 317-494-4572
fax 317-494-4572
fanwick@xray.chem.purdue.edu

Victor G Young, Chair-elect
Dept. of Chem.
Univ. of Minnesota
207 Pleasant St. SE
Minneapolis, MN 55455

tel. 612-625-6897
fax 612-626-7541
young@chemsun.chem.umn.edu

Doug Powell, Sec/Treas.
Dept. of Chem.
U. of Wisconsin, Madison
1101 Univ. Ave.
Madison, WI 53706-1322
tel. 608-262-3182
fax 608-262-0381
powell@chem.wisc.edu

SMALL ANGLE SCATTERING
Jill Trewhella, Chair
1417 Big Rock Loop
Los Alamos, MN 87544
tel. 505-667-2031103
fax 505-494-4572
jtrewhella@lanl.gov

Benjamin S Hsiao, Chair-elect
Central Res. & Dev.
E I DuPont De Nemours
PO Box 80302 ES
Wilmington, DE 19880-0302
tel. 302-695-4668
fax 302-695-1717
hsiao@esvax.dnet.dupont.com

Greg Beaucage, Sec/Treas.
Matl. Science & Engineering
Univ. of Cincinnati
498 Rhodes Hall ML12
Cincinnati, OH 45221-0172
tel. 513-556-3063
gbeaucage@uceng.uc.edu

Paul Schmidt, Member-at-Large
503 S Garth
Columbia, MO 65203
tel. 314-882-8241

SMALL MOLECULES
Bart Kahr, Chair
Dept. of Chemistry
Univ. of Washington
Box 351700
Seattle, WA 98195-1700
tel. 206-616-8195
fax 206-685-8665
kahr@chem.washington.edu

Richard Harlow, Chair-elect
7 Shull Drive Devon
Newark, DE 19711
tel. 302-695-2097

Fred Hollander, Sec/Treas.
Dept. of Chemistry
Univ. of California-Berkeley
Berkeley, CA 94720
tel. 510-642-8444
flieg@socrates.berkeley.edu

SYNCHROTRON RADIATION
Steven Burley, Chair
Rockefeller Univ.
1230 York Ave. Box 78
New York NY 10021
tel. 212-327 8336
fax 212-327-8337
burley@rockvax.rockefeller.edu

Thomas Koetzle, Chair-elect
Dept. of Chemistry
Brookhaven National Lab
Upton, NY 11973-5000
tel. 516-282-4384
fax 516-282-5815
koetzle@chm.chm.bnl.gov

Angus Wilkinson, Sec/Treas.
Dept. of Chem. & Biochem.
Georgia Inst. of Tech.
Atlanta GA 30332-0400
tel. 404-874-4036
fax 404-894-7452
angus.wilkinson@chemistry. gatech. edu

YOUNG SCIENTIST
Matt Redinbo, Chair
Biomol. Struct. Ctr.
University of Washington
Box 357742
Seattle, WA 98195
fax 416-926-6529
redinbo@u.washington.edu

Jeffrey Habel, Chair-elect
Dept. of Chem. & Biochem.
Georgia Inst. of Tech.
Atlanta, GA 30332
tel. 404-894-4075
fax 404-894-7452
jhabel@mindspring.com

Bianca Hovey, Sec/Treas.
Dept. of Biochemistry
Univ. of Washington
Box 357350
Seattle, WA 98195-7350
tel. 206-685-7047
tel. 206-685-7002
bhovey@u.washington.edu

ACA STANDING COMMITTEES

APPARATUS & STANDARDS
Ethan Merritt, Chair (96-98)
Box 357420
Dept. of Biological Structure
University of Washington
Seattle WA 98195-7420
tel. 206-543-1421
fax 206-865-7002
merritt@u.washington.edu

Bernie Santarsiero (97-99)
MCB 504 Stanley Hall
University of California
Berkeley, CA 94720
tel. 510-643-8234
fax 510-643-9290
bds@neuron1.berkeley.edu

Alan A. Pinkerton (98-00)
Dept. of Chemistry
Univ. of Toledo
2801 W Bancroft St.
Toledo, OH 43606-3390
tel. 419-530-4568
fax 419-530-4033
apinker@uoft02.utoledo.edu

CRYSTAL DATA & COMPUTING

Lee Brammer, Chair (96-98)
Dept. of Chemistry
University of Missouri
8001 Natural Bridge Rd
St. Louis MO 63121-4499
tel. 314-516-5345
fax 314-516-5342
lee.brammer@umsl.edu

Christophe Verlinde (97-99)
Biomolecular Structure Center
Box 357742
University of Washington
Seattle WA 98195-7742
tel. 206-543-8865
fax 206-685-7002
verlind@gouda.bmsc.washington. edu

Robert Von Dreele, (98-00)
LANSLE, MS H805
Los Alamos National Lab
Los Alamos, NM 87545
tel. 505-667-3630
fax 505-665-2676
vondreele@lanl.gov

CONTINUING EDUCATION
Douglas Ho, Chair (96-98)
Dept. of Chemistry
Princeton Univ. Frick Lab
130 Washington Rd
Princeton NJ 08544-1009
tel. 609-258-3160
fax 609-258-6746
ho@chemvax.princeton.edu

J. Krause Bauer, (97-99)
Dept. of Chemistry
University of Cincinnati
P.O. Box 210172
Cincinnati OH 45221-0172
tel. 516-556-9226
fax 513-556-9239
jeanette.krause@uc.edu

Raymond E Davis, (98-00)
Dept. of Chemistry
Univ. of Texas Austin
Austin, TX 78712-1167
tel. 512-471-4440
fax 512-471-8696
redavis@mail.utexas.edu

PUBLICATIONS

Stanley Cameron, Chair (96-98)
Dept. of Chemistry
Dalhousie University
Halifax NS B3H 4J3
CANADA
tel. 902-479-3506
fax 902-494-1310
cameron@ac.dal.ca

Ron Stenkamp (97-99)
Box 357420
Dept. of Biological Structure
University of Washington
Seattle, WA 98195-7420
tel. 206-685-1721
fax 206-543-1524
stenkamp@u.washington.edu

Douglas C Rees (98-00)
Dept. of Chemistry
California Inst. of Technology
147-75 CH
Pasadena, CA 91125
tel. 818-395-8393
fax 818-568-9430
rees@citray.caltech.edu

ROSTER - U.S. NATIONAL COMMITTEE FOR CRYSTALLOGRAPHY

Judith L. Flippen-Anderson, Chair (1999)
Lab. for the Structure of Matter
Naval Research Laboratory
Code 6030
Washington, DC 20375
tel. 202-767-3463
fax 202-767-6874
flippen@harker.nrl.navy.mil

Marvin Hackert, Vice-Chair (2002)
Dept. of Chem. & Biochem.
University of Texas at Austin
Austin, TX 78712
tel. 512-471-1105
fax 512-471-8698
m.hackert@email.utexas.edu

James A Kaduk, Secretary/Treasurer (2000)
Amoco Corporation
Amoco Research Center
150 W. Warrensville Road
P.O. Box 3011, MC F-9
Naperville, IL
tel. 630-420-4547
fax 630-420-5252
kaduk@amoco.com

Cele Abad-Zapatero (1999)
Abbott Laboratories, Inc.
46Y, AP-10, L-07
100 Abbott Park Rd.
Abbott Park, IL 60064-3500
tel. 847-937-0294
fax 847-937-2625
abad@mozart.pprd.abbott.com

Lonny E. Berman (1999)
Natl. Synch. Light Source
Brookhaven National Lab.
Bldg. 725D, P.O. Box 5000
Upton, New York 11973
tel. 516-344-5333
fax 516-344-3238
berman@bnl.gov

Lee Brammer (2000)
Dept. of Chemistry
Univ. of Missouri-St. Louis
8001 Natural Bridge Road
St. Louis, MO 63121-4499
tel. 314-516-5345
fax 314-516-5342
lee.brammer@umsl.edu

Charles W. Carter, Jr. (1998)
University of North Carolina
Dept. of Biochem. & Biophys.
Chapel Hill, NC 27599-7260
tel. 919-962-8326
fax 919-966-2852
carter@med.unc.edu

Connie Chidester (1998)
The Upjohn Company
301 Henrietta Street
Kalamazoo, MI 49007
tel. 616-385-7624
fax 616-385-7522
cgchides@am.pnu.com

Douglas L. Dorset (1998)
Electron Diffraction Dept.
Hauptman-Woodward Med. Res. Ins.
73 High Street
Buffalo, NY 14203-1196
tel. 716-856-9600
fax 716-852-4846
dorset@hwi.buffalo.edu

Howard M. Einspahr (2000)
Bristol-Myers Squibb Pharm. Res. Inst.
PO Box 4000 H23-03
Princeton, NJ 08543-4000
tel. 609-252-5267
fax 609-252-6030
einspahr@bms.com

Gary Gilliland (2000)
Chem. Sci. Tech. Lab.
Natl. Inst. of Stand. & Tech., Gaithersburg, MD
and Center for Adv. Res. in Biotech.
9600 Gudelsky Dr.
Rockville, MD 20850
tel. 301-738-6272
fax 301-738-6255
gary.gilliland@nist.gov

Richard L. Harlow(1999)
Central Res. and Dev.
E228/316d
E.I. DuPont de Nemours & Co., Inc.
Wilmington, DE 19880-0228
tel. 302-695-2097
fax 302-695-1351
harlow@esvax.dnet.dupont.com

Rick P. Millane (1998)
Whistler Center for Carbohydrate Res. and
Com. Sci. and Eng. Prog.
Purdue University
West Lafayette, IN 47907-1160
tel. 765-494-9272
fax 765-494-7953
rmillane@purdue.edu

Mark L. Rivers (1999)
The University of Chicago
Center for Adv. Rad. Sources
5640 South Ellis Avenue
Chicago, IL 60637
tel. 312-702-2279
fax 312-702-5454
rivers@cars3.uchicago.edu

Robert M. Sweet (2000)
Biology Department
Brookhaven National Lab
Upton, NY 11973
tel. 516-344-3401
sweet@bnl.com

Ex-Officio Voting Members

Philip Coppens, IUCr Past-President (1999)
Department of Chemistry
SUNY Buffalo
732 Natural Sci. and Math. Complex
Buffalo, NY 14260-3000
tel. 716-645-6800 ext. 2217
fax 716-645-6963
coppens@acsu.buffalo.edu

Michael Hart (1999), IUCr Executive Committee
Nat. Synch. Light Source
Brookhaven National Lab.
Upton, NY 11973
tel. 516-344-5939
fax 516-344-5842
hart1@bnl.gov

Jon Clardy, ACA Past-President (1998)
Abe Clearfield, ACA Vice-President (2000)

Jane F. Griffin, ACA Treasurer (2000)

Subcommittee on Interdisciplinary Activities (non-voting members)
Alex A. Chernov (1999)
Representing the American Assoc. for Crystal Growth
NASA/George C. Marshall Space Flight Center
Mail Code ES75
Marshall Space Flight Center AL 35812
tel. 205-544-9196
fax 205-544-8762
alex.chernov@msfc.nasa.gov

Gerald G. Johnson, Jr. (1998)
Representing the ICDD
IMRL - Penn. State Univ.
123 ROB/MRL.PSU
Univ. Park, PA 16802-4800
tel. 814-865-1637
fax 814-863-7845
johnson@psumrl1.psu.edu

NRC Staff Officer

Tamae Wong
National Research Council
2101 Constitution Ave., N.W.
Washington, DC 20418
tel. 202-334-2156
fax 202-334-2154
wong@nas.edu

Liason to the Board on Chemical Sciences and Technology
Joseph G. Gordon II
IBMResearch Division
K34/80-3Almaden Res. Cent.
650 Harry Road
San Jose, CA 95120-6099
tel. 408-927-1266
fax 408-927-2100 (BoxK34)
gordon@almaden.ibm.com

Call for Patterson Award Nominations
The generally triennial presentation of the A. L. Patterson Award will be made at the Buffalo, NY, meeting of the American Crystallographic Association in May, 1999. The A. L. Patterson Award, established in 1980, is to recognize and encourage outstanding research in the structure of matter by diffraction methods. This may include one or more of the following: (i) significant contributions to the methodology of structure determination, (ii) innovative application of diffraction methods, (iii) elucidation of biological, chemical, geological or physical phenomena using new structural information. There are no restrictions as to nationality, race, sex, religion, or membership of the ACA. The award is given in memory of Arthur Lindo Patterson, Senior Member, Institute for Cancer Research, Philadelphia, 1949-1966, whose most important contribution to crystallography was the function named after him. Previous recipients were: Wayne A. Hendrickson, 1981; Jerome Karle and Herbert Hauptman, 1984; David and Liselotte Templeton, 1987; Michael Woolfson, 1990; George Sheldrick, 1993; and Christer E. Nordman, 1997. The Award is for $3000, consisting of a monetary award of $1500, and $1500 in travel expenses to accept the award at an ACA Annual Meeting.

Nominations are invited from throughout the crystallographic community. They should be submitted in writing to any member of the committee. The major contributions of the nominee should be identified, with supporting documentation.
The closing date for nominations is July 1st, 1998; earlier nominations would be welcomed. The members of the 1999 Patterson Award Committee are:
Dr. Lee Brammer (Chair)
Dept. of Chemistry
Univ. of Missouri-St. Louis
8001 Natural Bridge Road
St. Louis, MO 63121-4499
lee.brammer@umsl.edu

Dr. Helen M. Berman
Dept. of Chemistry
Wright & Rieman Labs
Rutgers University
PO Box 939
Piscataway, NJ 08855-0939
berman@adenine.rutgers.edu

Dr. Charles W. Carter
Dept. of Biochem. & Biophys.
University of North Carolina - CB7260
Chapel Hill, NC 27599-7260
carter@pasteur.med.unc.edu

Dr. Judith A. Kelly
Dept. of Molec. & Cell Biol.
University of Connecticut
75 N. Eagleville Road
Box U125
Storrs, CT 06269-3125
kelly@uconnvm.uconn.edu

Call for Nominations for the USNCCr
The USNCCr will be electing 4 new regular members in 1998 to serve for the 3 year period 1999-2002. If you would like to nominate someone, including yourself, to serve on the Committee, please contact one of the following USNCCr members:
Lonny Berman, Chair berman@bnlx17.nsls.bnl.gov
Cele Abad-Zapatero: cele.abadzapatero@abbott.com
Dick Harlow: harlow@esvax.dnet.dupont.com
Mark Rivers: rivers@cars3.uchicago.edu

International Union of Crystallography - Nominations for the Ewald Prize
The International Union of Crystallography is pleased to invite nominations for the Ewald Prize for outstanding contributions to the science of crystallography. The Prize is named after Prof. Paul P. Ewald in recognition of his significant contributions to the foundations of crystallography and to the founding of the International Union of Crystallography. Professor Ewald was the President of the Provisional International Crystallographic Committee from 1946 to 1948, the first Editor of the IUCr publication Acta Crystallographica from 1948 to 1959 and the President of the IUCr from 1960 to 1963.
The Prize consists of a medal, a certificate and a financial award, and is presented once every three years during the triennial International Congresses of Crystallography. The recipients to date are as follows: 1987 Prof. J.M. Cowley and Dr. A.F. Moodie, 1990 Prof. B.K. Vainshtein, 1993 Prof. N. Kato, 1996 Prof. M.G. Rossmann. The fifth Prize, for which nominations are now being invited, will be presented at the XVIII Congress in Glasgow, UK, in August 1999.
Scientists who have made contributions of exceptional distinction to the science of crystallography are eligible for the Ewald Prize, irrespective of nationality, age or experience. The Selection Committee will give careful attention to the nominations of outstanding scientists who have not yet won a major prize. Either an exceptionally distinguished scientific career or a major scientific accomplishment may be recognized. Current members of the Selection Committee and the President of the IUCr are not eligible. No restrictions are placed on the time or the means of publication of the nominee's contributions. The Prize may be shared by more than one contributor, but not more than three, to the same scientific achievement.
Nominations for the Ewald Prize should be submitted in writing, preferably using the Ewald Prize Nomination Form and accompanied by supporting documentation, to the Executive Secretary of the International Union of Crystallography, 2 Abbey Square, Chester CH1 2HU, England, from whom copies of the Nomination Form and the names of the Selection Committee may be obtained. The closing date for nominations is 31 August 1998.

Isabella Karle Wins ACS Award for Peptide Chemistry
The American Chemical Society has presented the Ralph F. Hirschmann Award in Peptide Chemistry to Isabella L. Karle, U.S. Naval Research Laboratory. The award is sponsored by Merck Research Laboratories and will be given in March at the 215th national ACS meeting in Dallas.
International Centre for Diffraction Data Announces Crystallography Scholarship Award Recipients
The International Centre for Diffraction Data is pleased to announce the awarding of five Crystallography Scholarships for 1998. They are: Ekaterina Anokhina from Wake Forest University, Winston-Salem, North Carolina; Nathalie Audebrand from the Universite de Rennes I, Rennes, France; Susanne C. Feil from St. Vincent's Institute of Medical Research, Victoria, Australia; Christopher D. Theis from The Pennsylvania State University, University Park, Pennsylvania; and K. Scott Weil from Carnegie Mellon University, Pittsburgh, Pennsylvania.
Ekaterina Anokhina's studies focus on "Niobium Oxochloride Cluster Compounds: a Quest for Correlations between Configuration of the Clusters, Framework Topology and Properties." Nathalie Audebrand will continue her research of "Structure, Microstructure and Temperature-dependent Diffraction Studies of New Cerium-based Precursors and Related Oxides." The exploration of "Structural and Functional Aspects of Pore-forming Proteins by X-ray Crystallography and Molecular Biology" will be conducted by Susanne Feil. Christopher Theis will study "Ferroelectric Superlattices and Higher n Aurivillius Phases Grown by MBE". "Investigation of the Formation, Structure, and Magnetic Behavior of Compounds in the Nickel- Molybdenum-Nitrogen System" will be researched by K. Scott Weil.

Wayne Hendrickson Receives Hollaender Award
The National Academy of Sciences has selected 15 individuals to receive awards for their outstanding contributions to science. Presentations will be made on April 27 at a ceremony in Washington, D.C., during the Academy's 135th annual meeting. The Alexander Hollaender Award in Biophysics - a prize of $15,000 awarded every three years for outstanding contributions in biophysics - goes to Wayne A. Hendrickson, investigator, Howard Hughes Medical Institute, and professor, Department of Biochemistry and Molecular Biophysics, Columbia University College of Physicians and Surgeons, New York City. Hendrickson was chosen "for his contributions to macromolecular crystallography, in the development of robust methods of phasing and refinement, and in determination of complex and biologically important structures." The award will be presented for the first time this year.

Daniel Everett Appleman 1931-1998
Daniel Appleman died at age 66 on January 2, 1998. Thus is ended an extraordinary career in mineralogy, crystallography, and museum design. He leaves behind his wife Peggy and his daughter Rebecca.
Daniel was born April 11, 1931, in Berkeley, California. He and his two brothers grew up in a professional environment (his father was Professor of Botany at UCLA). In this stimulating background, Daniel earned his Bachelor of Science degree at California Institute of Technology in 1953. He then entered graduate school in the Department of Geology at Johns Hopkins University. While working on a thesis for a Ph.D. degree (awarded 1956) he joined the U. S. Geological Survey in 1954, where he stayed until 1974. In this laboratory he carried out crystal structure and crystal chemical studies in uranium mineralogy, comprehensive structural studies of the pyroxene-type minerals, among other topics. An accomplished computer programmer, he is noted for the creation (with Evans) of the Appleman program for the refinement of unit cell parameters by least-squares analysis of X-ray powder diffraction data, which is still used today world-wide.
In 1974 he moved to the Smithsonian Institution where he became Chairman of the Division of Mineral Sciences. While there he substantially improved the staff and facilities of this laboratory, and continued his mineralogical investigations. Among his outstanding achievements here was the refinement (with John Konnert) of the structure of low-temperature tridymite, with 240 unique atoms, 732 parameters in space group F1 (with interatomic distance restraints and fourfold twinning, R = 0.064). In his last years at the Natural History Museum he served as Associate Director for Science. In this capacity he initiated a complete renovation of the Mineral Hall. After two years of construction the exhibit was reopened September 17, 1997 as the Hooker Hall of Geology, Gems and Minerals, which has since attracted enormous attention.
In 1993 Daniel was called to serve as Vice-President of the Cranbrook Institute in Bloomfield Hills in Michigan (near Detroit) to direct the Science Institute. This famous liberal arts school has an outstanding science museum, and Dan set to work to design and build a new wing. It must have given Daniel much satisfaction to sit in his office and look out of the window across the courtyard and watch the building take shape (as well as to attend the opening of the Hooker Hall at the Smithsonian!). It is a tragedy that cancer, which he fought heroically for a year, overtook him before it was completed.
The spectacular Hooker Hall at the Smithsonian Institution and the Science Museum at the Cranbrook Institute are both well worth a visit, and anyone who does visit these places should give a silent prayer of thanks to Daniel Appleman for making these marvelous displays possible.
Howard T. Evans, Jr.

Petition Concerning Coordinate Holds in the PDB

Alex Wlodawer is circulating the following petition to generate comments and support for changes in the Protein Data Bank's policy on withholding coordinates for up to a year after submission. Any supporting or opposing messages should be sent to him at: wlodawer@ncifcrf.gov or faxed to 301-846-6128. If he finds sufficient support, he will submit the petition to the Commission on Biological Molecules of IUCr.
To: Commission on Biological Molecules, IUCr
We, the undersigned, would like to request a revision of the IUCr policy on publication and deposition of data from crystallographic studies of biological macromolecules (Acta Cryst. A45, 658 (1989). It is our intention that if the policy gets revised, the new rules will be communicated to granting agencies and to scientific journals, in order to be universally accepted.

The current policy has been implemented on the basis of the discussions which had taken place a decade ago. In the meantime, there has been an incredibly rapid increase in the rate of determination of 3D structures of biomacromolecules, as reflected by the deposition of a new structure in the Protein Data Bank (PDB), on average, every five hours. Unfortunately, in parallel, an increasing proportion of depositors take advantage of the PDB's policy of allowing structures to be kept 'on hold' for up to a year after coordinate deposition. Consequently, as many as 45% of newly deposited structures are not available when the relevant papers are published.
When the issue of deposition was debated by the community ten years ago, the time needed to solve a macromolecular structure was often measured in years, and was rarely less than one year. The time needed for detailed analysis of such structures was also fairly long. The one-year hold on coordinates was therefore instituted to allow the authors to reap the fruit of their tremendous investment of time and effort. Due to recent advances in protein expression and purification, crystallization procedures, X-ray instrumentation, and computer software, the time needed to solve a structure is often shorter than the allowed hold period. In light of such developments, it is very difficult to justify withholding coordinates for any period once the paper has been published.
Biomolecular structure analysis has indeed succeeded in bringing 3D structures to the forefront of molecular biological research. This success has expanded both the interest in and utility of the information being deposited in the PDB. The molecular modeling community has grown and evolved considerably due to the expansion of this source of experimental data. The value of the data rests in their availability to the broader community. Methods are continuously being developed to analyze new structures and their relationships to the collection of existing structures. New uses for these data, such as statistical potentials for folding and threading calculations, and interface recognition tools, are evolving rapidly. No single research group can fully exhaust this wealth of information. The value of the resource grows proportionally to the timeliness of the data and to the number of scientists who have access to them. 3D structural information is also a crucial link elucidating the role of a translated region of a DNA sequence of unknown function.
We feel most strongly that the time has come to change the rules of deposition so as to ensure that the coordinates are released concomitantly with publication of the paper(s) describing the structure. We are convinced that without access to the coordinates, the structures cannot be utilized for comparison with other proteins, for theoretical analysis or, more and more importantly, for drug design. We propose that coordinates deposited at the PDB should be marked as either "for immediate release" or "to be released upon publication". We also recommend that the maximum hold for primary data, i.e., X-ray structure factors, and NMR-based restraints, be reduced from 4 years to 1 year. These changes would bring macromolecular crystallography into line with the requirements of other fields, such as gene sequencing, which have never allowed extended hold periods.
Dr. Alexander Wlodawer

Macromolecular Structure Laboratory

NCI-FCRDC, P.O. Box B

Frederick, MD 21702

wlodawer@ncifcrf.gov

Phone (301) 846-5036 fax -6128

Vote For or Against the One-Year Hold on the Web
To further the discussion concerning the one-year hold, Nature Structural Biology is hosting a vote on the issue at its website. If you have missed the flurry of electronic notices and discussion and you wish to participate in the vote, please investigate the website. The URL for the site of the vote is:
http://us.nature.com/survey/nsb_poll.nclk
Guy Riddihough (Editor) and Nature Structural Biology deserve our thanks for providing an opportunity for increased public input on this policy.

Meeting Site Changes for ACA 98
Due to circumstances beyond our control, the site of the 1998 ACA Annual Meeting has been changed. The meeting will be held at the Hyatt Regency Crystal City, in Arlington, Virginia. The Hyatt Regency is adjacent to and offers free shuttle service to Washington National Airport and the METRO subway. It is 32 miles from Dulles International Airport. Overlooking the Potomac River, it is 5 minutes from historic Old Town Alexandria, and the Pentagon, and 10 minutes from downtown Washington, the US Capitol, the Smithsonian, the White House and Georgetown. The scientific program for the meeting will remain the same. Room rates at the Hyatt will be $115 (single, double, triple or quad) per night + 9.875% tax. A hotel reservation form is available on our web site. All ACA members should have received a revised Call for Papers. Contact the ACA's Buffalo office if you need one. Please check the meeting web site for periodic updates concerning the meeting: http://www.hwi.buffalo.edu/ACA/.

Mid-Atlantic Protein Crystallography Workshop
The Mid-Atlantic protein crystallography workshop will be held June 11-13, 1998 at Johns Hopkins University. For further information, please contact Cynthia Wolberger, Department of Biophysics/HHMI, Johns Hopkins School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205-2185. tel. 410-955-0728, fax 410-955-0637.

Summer School on Neutron Scattering

A Summer School on Neutron Scattering will be held at Chalk River Laboratories, Ontario, Canada, 22-26 June 1998. For further information, see http://neutron.nrc.ca/SS98.htm or contact Zin Tun, Neutron Program for Materials Research (NRC), Chalk River Laboratories, Chalk River, Ontario, Canada, K0J 1J0. tel. 613-584-8811, ext. 3994 fax 613-584-4040 e-mail zin.tun@nrc.ca.

We gratefully acknowledge the continued support from our ACA CORPORATE MEMBERS
Area Detector Systems Corporation, Poway, California
B. A. Frenz & Associates, College Station, Texas
Biblotek Technische Hochschule, Hannover, Germany
Blake Industries, Inc., Scotch Plains, New Jersey
Brookhaven National Laboratory, Upton, New York
Bruker Analytical X-Ray Instruments, Inc., Madison, Wisconsin
Charles Supper Company, Inc., Natick, Massachusetts
Crystal Logic, Inc., Los Angeles, California
Cyberlab, Brookfield, Connecticut
Digital Equipment Corporation, Maynard, Massachusetts
Diversified Scientific, Inc., Birmingham, Alabama
Fuji Medical Systems USA, Inc., Stamford, Connecticut
Hampton Research, Laguna Hills, California
HHMI/Sigler Lab, New Haven, Connecticut (new member for 1998)
J. Schneider Electrotechnik Gmbh, Offenburg, Germany
Luxel Corporation, Friday Harbor, Washington
Molecular Structure Corporation, The Woodlands, Texas
Nonius Company, Bohemia, New York
Osmic, Inc., Troy, Michigan
PerSeptive Biosystems, Inc., Framingham, Massachusetts
Protein Solutions, Charlottesville, Virginia
Scientific Information Service Inc., Larchmont, New York

NSLS Workshop on Using Powder Data to Solve Crystal Structures: May 18th, 1998
The ab-initio solution of unknown crystal structures from powder diffraction data is a rapidly evolving field that has seen many exciting advances during the past few years. High-resolution synchrotron powder techniques have played a major role in this area, especially for framework structures such as zeolites, fullerene derivatives and other molecular compounds, and small organic molecules of pharmaceutical significance. Analysis by traditional Patterson and direct methods has been augmented by a variety of other techniques, including methods based on maximum entropy, Monte Carlo, simulated annealing and genetic algorithms. This workshop will feature many of the leading experts in Europe and the USA, and provide a comprehensive, state-of-the art, overview which should be of outstanding interest to the powder diffraction community. Registrants are encouraged to submit contributions to a poster session on structure solution and refinement to be held concurrently with the workshop.
The workshop will be held as part of the NSLS Annual Users' Meeting, which will begin the following day, and workshop participants should register separately for this meeting if they wish to attend it as well.
For further information, please contact: D. E. Cox, Physics Department, Brookhaven National Laboratory, Upton, NY 11973-5000, tel. 516-344-3818, fax 516-344-2739, E-mail: cox@bnlx7a.nsls.bnl.gov.

Rietveld Method Short Course May 4 - 6, 1998 Atlanta, Georgia
The Rietveld method is widely recognized to be uniquely valuable for crystal structure and related analyses of nearly all crystalline materials not available as single crystals. This 3-day intensive course will be conducted by Professors R.B. Von Dreele and R.A. Young, both well known in the field. The course will deal with the principles and techniques of Rietveld analysis and with avoiding or overcoming problems encountered in the use of it. The teaching system involves morning lectures, supervised individual hands-on experience running the Rietveld refinements on PC-type computers in the afternoon, much student-teacher interaction and discussion, and availability of the computers at other times for further individual practice. The student will have a choice of using either of the two most widely used Rietveld programs, DBWS and GSAS. Both the well grounded beginner and the moderately experienced user should find the course valuable.
The course is conducted by Georgia Tech Continuing Eduction and costs $896 (includes monograph and copies of computer programs and examples). For more information: Contact Distance Learning, Continuing Education and Outreach, Georgia Institute of Technology, Atlanta, Georgia 30332-0385, Phone: 404/894-2547, e-mail: conted@gatech.edu. WWW - http://www.conted.gatech.edu

ACA Course for Crystallographers
The seventh annual ACA Summer Course for Crystallographers will be a 12 day course held from July 5 to July 16, 1998 at the University of Georgia, Athens GA.
This year the course will be expanded to include more time for macromolecular crystallography. The first 8 days will be devoted to lectures and laboratory sessions for basic crystallography. In the afternoon of day 9 the students will give short presentations on the structures they worked on during the first part of the course. In the evening of day 9 and continuing through day 12 there will be lectures and laboratory sessions for macromolecular crystallography.
The basic crystallography part of the course will include lectures on the basic mathematics and physics behind structural analysis, the methods of structure solution, the refinement of atomic parameters and presentation and analysis of the results of structure determination. The laboratory part of the course will teach the students to select and mount crystals, determine unit cell dimensions and collect data on modern diffractometers. They will learn to use modern software to determine space groups and solve and refine structures and compare the final structures with previously determined structures. Finally they will use software to prepare plots and reports of their structures.
The macromolecular part of the course will include lectures on crystallization, data collection strategies, determination of heavy atom sites, structure solution by MIR, SIR, MAD, SAS and molecular replacement techniques, chain tracing and structure model building. Lectures concerning refinement methods and use of databases will also be included. The laboratory part of the course will include demonstrations of the methods for crystallization of proteins, the methods for phase calculations using MIR/SIR/MAD/SAS and the methods for model building and refinement.
The University of Georgia (UGA) has equipment from all four major vendors (Enraf Nonius and Bruker diffractometers in Chemistry and Rigaku, MarResearch and Bruker area detectors in Biochemistry and Molecular Biology). The associated computers and software are available in each of these departments.
The lecturers will be the two co-organizers: Prof. Bi-Cheng Wang (UGA) and Dr. Robert A. Sparks (Consultant, Bruker Corp.), together with Dr. John Rose and Prof. Gary Newton (UGA) and several lecturers from universities outside of UGA. In addition experienced laboratory instructors will be available in each of the crystallography laboratories.
A revised set of lecture notes will be given to each student.
Tuition for the course will be $600. Admission will be limited to approximately 35 - 40 students. Six full-tuition and ten half-tuition scholarships will be provided on a competitive basis. The criteria for these awards are (1) expected benefits from the course, (2) qualification and (3) motivation. Accommodations have been reserved at UGA from the evening of July 4; the rate for these air-conditioned rooms will be $30 per day single, or $19 per day double occupancy. Student housing is only a short walk from where the lectures will be given and from the laboratories with the X-ray equipment that will be used.
Applications should be made on forms available from Dr. John Rose, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602. Tel. 706-542-1750; fax 706-542-3077; E-mail: rose@BCL4.biochem. uga.edu.
Electronic application forms are available from the UGA BioCrystallography WWW server: http://www.uga.edu/~biocryst/ACASC98.html
APPLICATION FORMS MUST BE COMPLETED AND RETURNED TO PROF. WANG NO LATER THAN MAY 31, 1998.
Bi-Cheng (B.C.) Wang, Ph.D.
Professor, Department of Biochemistry & Molecular Biology
Ramsey-GRA Eminent Scholar in Structural Biology
B204A, Life Sciences Building
University of Georgia
Athens, GA 30602-7229
tel. 706-542-1747
fax 706-542-3077
E-mail wang@BCL1.bmb.uga.edu
Web Site: http://www.uga.edu/~biocryst

Polycrystal Book Service - NEW BOOKS OF INTEREST TO CRYSTALLOGRAPHERS
Likelihood, Bayesian, Interference and Their Application to the Solution of New Structures, ed. by G. Bricogne & C.W. Carter (ACA, 1996, 166 pages, $25 paper) is Transactions of the ACA, Volume 30, 1994, from the symposium entitled "Entropy, Likelihood, Bayesian Inference, and Their Application to Solution of New Structures," at Atlanta, GA, June 25 - July 1, 1994. Full table of contents can be seen at the Polycrystal Website.
Structural Tools in Organometallic and Coordination Chemistry, ed. by L. Brammer (ACA, 1997, 96 pages, $25.00 paper) is Transactions of the ACA, Volume 31, 1995, from the symposium of the same name, Montreal, Quebec, July 23-28, 1995. Full table of contents can be seen at the Polycrystal Website.
RNA Structure and Function, ed. by R.W. Simons & M. Grunberg-Manago (Cold Spring Harbor, 1997, 726 pages, $145.00) is CSH Monograph 35, which encompasses the experimental approaches to define RNA structure and its influence on functions, in an up-to-date survey of the field.
World Directory of Crystallographers and other scientists employing crystallographic methods, 10th edition, ed. by Y. Epelboin (Kluwer, 1997, 310 pages, $29.50 paper) has been published and we now have copies. The database is also accessible via the World-Wide Web.
Time-Resolved Diffraction, by J.R. Helliwell & P.M. Rentzepis (Oxford, 1998, 464 pages, $160.00) is Oxford Series on Synchrotron Radiation Vol. 2, and covers X-ray, neutron and electron time-resolved diffraction from gases, liquids, amorphous solids, fibers and crystals, using examples from the disciplines of chemistry, biology, physics and materials science.
Crystallographic Instrumentation, by L.A. Aslanov, G.V. Fetisov & J.A.K. Howard (Oxford, 1998, 336 pages, $120.00) IUCr Monographs on Crystallography Vol. 7, is due out in June. It presents fundamentals of radiation, diffraction experiments, and diffractometry, then details single crystal diffractometry, data collection & processing, data reduction and error correction, and defects in crystals and their influence on structure analysis.
Dana's New Mineralogy: The System of Mineralogy of James Dwight Dana and Edward Salisbury Dana, 8th Edition, by R. V. Gaines, H.C.W. Skinner, E.E. Foord, B. Mason, & A. Rosenzweig (Wiley, 1997, 1872 pages, $295.00), offers descriptions of all the more than 3000 recognized mineral species, emphasizing structure, but also including locations, and has an extensive cross-index. Yes, it has finally been released!!
The World of Opals, by A.W. Eckert (Wiley, 1997, 464 pages, $75.00) is the first comprehensive book on opals in some 30 years, and contains 22 color plates, many tables, an up-to-date survey of the world's opal fields, and an extensive bibliography and index. The book is especially interesting for its historical descriptions of this most colorful and least crystalline of the five precious gemstones - in fact, opal's microstructure was only initially determined in the 1960's.
Crystallography and Crystal Chemistry, 2nd Printing, with minor corrections, by F.D. Bloss (Mineralogical Society of America, 1994, 545 pages, $30.00 paper) has only recently come to our attention. This is an inexpensive reprint of the original edition from 1971 which has been long out of print. It is especially valuable as a supplemental text for any course in crystallography and diffraction, especially for mineralogy, materials science, solid state physics, metallurgy, and chemistry. Bloss's treatment of symmetry beginning with external symmetry followed by internal symmetry of crystals, and his treatment of tensors and properties have been described as perhaps the most understandable yet!
The Many Faces of RNA, ed. by D. Eggleston, C. Prescott & N. Pearson (AP, 1997, 240 pages, $99.95) is the subject of the 8th SmithKline Beecham Pharmaceuticals Research Symposia, and emphasizes the interplay among biology, chemistry, genomics, and molecular biology, exploring RNA as a therapeutic target and as a tool, along with chemical, computational, and structural investigations.
Cell Biology: A Laboratory Handbook, 2nd ed., ed by J.E. Celis (AP, 1997, 2400 pages, $179.95) is comb bound in four volumes, in sections entitled (in part): Cell and Tissue Culture; Viruses; Organelles & Cellular Structures; Assays; Antibodies; Light Microscopy and Contrast Generation; Electron Microscopy; Intracellular Measurements; Cytogenetics; Transgenics; Transfer of Macromolecules; Expression Systems; and Proteins.
Quasicrystals: A Primer, 2nd Edition, by C. Janot (Oxford, 1997, 409 pages, $55.00 paper) is a more reasonably priced version of the 1994 hardbound primer, still available for $100.00.
Molecular Symmetry and Group Theory, by R.L. Carter (Wiley, 1997, 320 pages, $42.95)
Chemical Bonding: A Dialogue, by J.K. Burdett (Wiley, 1997, 172 pages, $45.00 paper) is a question and answer style text which addresses the nature of the chemical bond, D orbitals, Benzene and the Jahn Teller effect, among others.
The Theory of Intermolecular Forces, by A.J. Stone (Oxford, 1997, 280 pages, $50.00 paper) describes the advanced mathematical techniques which have now surpassed the simple empirical models. International Series of Monographs on Chemistry Vol. 32.
Physical Chemistry of Surfaces, 6th ed. by A.W. Adamson and A.P. Gast (Wiley, 1997, 784 pages, $79.95) contains a full update with 35% new material.
Computer Modeling and Simulations of Complex Biological Systems, 2nd Ed., ed. by S.S. Iyengar (CRC, 1997, 224 pages, $79.95)
Atlas of Immunology, by J.M. Cruse & R.E. Lewis (CRC, 1997, 352 pages, $69.95) contains over 1000 illustrations of molecular and morphological structures.
Separation and Purification by Crystallization, ed. by G.D. Botsaris & K. Toyokura (ACS-Oxford, 1997, 298 pages, $99.95) includes crystallization of polymorphs, separation of chiral compounds, and crystallization of amino acids, proteins and pharmaceuticals.
Pearson's Handbook: Desk Edition, ed. by P. Villars (ASM, 1997, 2 Volumes, $775.00) contains 27,686 entries, the "best" reference for each phase, and is updated through 1995. It is about half the size and price of the 1991 four volume 50,000 entry set.
An Introduction to Error Analysis: The Study of Uncertainties in Physical Measurements, 2nd Edition, by J.R. Taylor (University Science Books, 1997, 327 pages, $44.50 Hardbound, $29.50 paper) is an expanded version of the very popular 1982 edition, noted by its cover photo of a very distressed steam locomotive. The new edition includes twice as many problems with level of difficulty indicated, many new figures, and substantial additions to the text which was already notable for its clarity.
The Faber Book of Science, ed. by J. Carey (Faber & Faber, 1995, 528 pages, $29.95) has also only recently come to our attention. This collection of 102 short essays from the past five hundred years of science (and technology) writing will provide delight for scientists and laypeople for years to come. The scope is a vast as is science itself, from Leonardo to Azimov, and holds special interest for crystallographers in several essays: "Chains and Rings: Kekule's Dreams;" "God and Molecules;" "The Discovery of X-rays;" "Why Light Travels in Straight Lines;" "Negative Predictions;" "Seeing the Atoms in Crystals;" and "The Plan of Living Things," all by authors that will be familiar to ACA members.
Thermodynamics of Crystals, by D.C. Wallace (Dover, 1998, 512 pages, $14.95 paper) will be out in June as a reprint with minor corrections of the 1972 Wiley text covering equilibrium thermodynamics of perfect crystals in a form suitable for undergraduates in materials science ands solid state physics.
Natural Art Forms: 120 Classic Photographs, by K. Blossfeldt (Dover, 1998, 128 pages, $10.95) due out in April, is an unabridged reproduction of the 1932 German edition containing 120 full page black-and-white plates of botanical subjects. His other well-known work, Art Forms in the Plant World, is also still available as a Dover paperback in its sixth printing for $9.95.
Organizing Scientific Meetings, by A. Epple (Cambridge, 1997, 184 pages, $14.95 paper) is a very nice compendium of all the details one should consider before being foolish enough to "volunteer" to organize a scientific meeting! In concise chapters, tables of check lists, and sample letters, the author identifies common problems and offers solutions - an indispensable guidebook.
Career Renewal: Tools for Scientists and Technical Professionals, by S. Rosen & C. Paul (AP, 1997, 360 pages, $24.95 paper) is a practical guide to finding a new profession or a better job in your current profession. It contains career choice exercises, resume guidelines, WWW job search advice, and resources for networking, mentoring, recruiting, interviewing, and negotiating salary.
Alternative Careers in Science: Leaving the Ivory Tower, ed. by C. Robbins-Roth (AP, 1998, 200 pages, $29.95 paper) due out in March.
We're ready for another Polycrystal Rare Book Website Auction! We'll have about 70 old warhorses for sale - they go to the highest bidders over a minimum bid, and this auction will run until about two weeks before the ACA Meeting in Washington - check the website for more information.
All items can be ordered from Polycrystal Book Service, P.O. Box 3439, Dayton, Ohio 45401, U.S.A., Telephone and FAX 937-223-9070. Prepayment is appreciated, but not required. We will send books with an invoice, and prefer to be paid by check to avoid the service change from credit card companies. However, charge cards (MC/VISA/AE; sorry, NOT DC or Discover) are also accepted! Purchase orders are gladly accepted. Please include the appropriate shipping charge: Orders to $20/$4; $20 to $50/$5; $50-$100/$6; $100-$200/$7; over $200 or foreign orders, please inquire. Remember that Polycrystal can order ANY book from ANY publisher ANY time of the year - we distribute for over 200 publishers! Volume and classroom discounts are available. Orders and inquiries are possible now by e-mail: polybook@dnaco.net Visit our Homepage: http://www.dnaco.net/~polybook

Meeting Calendar
In order to conserve space and paper, contact points for most meetings announced in previous newsletter issues will not be repeated. More complete information can be found in back issues of the newsletter.
MAY 1998
3-8 Seventh International Conference on Crystallization of Biological Macromolecules, Granada, Spain . Check the IUCr website for further information.
18 NSLS Workshop on Using Powder Data to Solve Crystal Structures, Upton, New York. Contact: D. E. Cox, Physics Department, Brookhaven National Laboratory, Upton, NY 11973-5000, tel. 516-344-3818, fax 516-344-2739, E-mail: cox@bnlx7a.nsls.bnl.gov.
28 - June 7 27th Intl. School of Crystallography. Implications of Molecular and Materials Structure for New Technologies, Erice, Sicily. Web site: http://www.ccsem.infn.it
JUNE 1998
1-6 Tenth International Summer School on Crystal Growth, Rimini, Italy. Web site: http://www. maspec.bo.cnr.it/CG/school_cg.html
11-13 Mid-Atlantic Protein Crystallography Workshop, Baltimore Maryland, Johns Hopkins University. Contact: Cynthia Wolberger, Department of Biophysics/HHMI, Johns Hopkins School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205-2185. tel. 410-955-0728, fax 410-955-0637.
20-25 Xth International Symposium on Molecular Recognition and Inclusion, Warsaw, Poland. E-mail: ismri-10@ichf.edu.pl or klatrat@ichf.edu.pl.
22-26 Summer School on Neutron Scattering, Chalk River Laboratories, Ontario, Canada. Website: http://neutron.nrc.ca/SS98.htm. Contact: Zin Tun, Neutron Program for Materials Research (NRC), Chalk River Laboratories, Chalk River, Ontario, Canada, K0J 1J0. tel. 613-584-8811, ext. 3994 fax 613-584-4040 e-mail zin.tun@nrc.ca.
JULY 1998
5-16 Seventh ACA Summer Course on Crystallography, University of Georgia, Athens, GA. Check the ACA web site for details: http://www.hwi.buffalo.edu/ACA/.
13 - 17 IUPAC Macro 98: 37th International Symposium on Macromolecules.
18-23 ACA'98 Arlington, VA, Program Chair: Louis Delbaere (Univ. of Saskatchewan). Local Co-chairs: Winnie Wong-Ng (NIST) and John Barnes (NIST). See the call for papers or ACA website for details.
26-31 Twelfth International Conference on Crystal Growth, Jerusalem, Israel. Web site: http://www. technion.ac.il/~iccg12
AUGUST 1998
3-8 47th Denver X-ray Conference, Antlers Doubletree Hotel, Colorado Springs, CO. Contact: Manager, Schools and Conferences, ICDD, 12 Camput Boulevard, Newtown Square, PA 19073-3273. FAX: 610-325-9823. E-mail: dxc@icdd.com
4-8 Sixth International Conference on Biophysics & Synchrotron Radiation. Argonne, IL. Contact Keith Moffatt, University of Chicago. E-mail moffat@cars.uchicago.edu Web site: http://www.aps.anl.gov/conferences/bsr
10-14 IMA'98 17th General Meeting, Int. Mineralogical Assoc., Toronto, Canada. Web site: http://www:geology. utoronto.can/IMA98
22-25 Sixth European Powder Diffraction Conference (EPDIC-6). E-mail: ungar@ludens.elte.hu
DECEMBER 1998
6-10 Molecular Graphics and Modelling Society 1998 International Meeting. Contact: P. Graber, The Scripps Research Inst. MB-5, 10550 N. Torrey Pines Rd, La Jolla CA 92037, 619-784-2526; mgms98@ scripps.edu. Web site: http://www.mgmsoa.org.
MAY 1999
22-27 ACA'99. Buffalo, NY. Local Chair: David Smith (HWI) smith@hwi.buffalo.edu, Program Chair: Steve Ealick (Cornell) see3@cornell.edu
.
AUGUST 1999
4-13 18th IUCr General Assembly and Intl. Congress of Crystallography. Glasgow, Scotland. Contact: C. J. Gilmore, Dept. of Chem, U. of Glasgow, Glasgow G128QQ, Scotland. FAX: 41-330-4418, e-mail iucr99@chem.gla.ac.uk Check the IUCr website for further details.
JULY 2000
22-27 ACA '00 St. Paul, MN Local Chair: Bill Gleason (UMN), Program Chair: Doug Ohlendorf (UMN).
JULY 2001
21-26 ACA '01 Los Angeles, CA
AUGUST 2002
6-15 19th IUCr General Assembly and Intl. Congress of Crystallography. Jerusalem, Israel. Contact:J. Bernstein, Ben Gurion University, Beer Sheva, Israel

Contributors to This Issue

Wade Adams, Lee Brammer, Penny Codding, Marcia Colquhoun, Dave Cox, Lee Daniels, Howard Evans, Judy Flippen-Anderson, Isabella Karle, Sally Lunge, Guy Riddihough, Ron Stenkamp, Zin Tun, B.C. Wang, Alex Wlodawer, Cynthia Wolberger.

Positions Available
It is expected that the employers listed in this publication are equal opportunity employers who wish to receive applications from qualified persons regardless of age, national origin, race, religion, sex or physical handicaps. Please inform the Editor when the positions are filled, and of any positions that do not give opportunities to all applicants. Ads will appear in two successive newsletters unless the Editor is notified that the advertisement should be continued longer or discontinued earlier.
For the most up-to-date listings check the ACA Home Page under the Positions Vacant heading. http://www.hwi.buffalo.edu/ACA/

Protein Crystallography
A position in protein crystallography is available for structure analysis of several enzymes involved in bacterial antibiotic resistance (see Chem. & Biol. 3:937 and Biochemistry 36:2531). Experience with crystallization, low-temperature data collection, synchrotron facilities, and phasing methods is desirable. The University is located in a pleasant rural area only 1 1/2 hr from Boston and less than 1 hr from recreation areas along Long Island Sound. Applicants should send their resume and names of 3 references by May 15, 1998, to: James Knox, Department of Molecular Biology, The University of Connecticut, Storrs, CT 06269-3125. Additional information is available at 860-486-3133 or knox@uconnvm.uconn.edu.

Post Doctoral Fellow
A post-doctoral vacancy is available for a person with interest in crystallography, electron microscopy, biochemistry and molecular biology. The research will be primarily in cryo EM reconstructions for ongoing projects in the laboratories of Timothy Baker, Richard Kuhn, Michael Rossmann and Thomas Smith. Some experience in cryo EM data collection and analysis is particularly desirable, but in its absence we would be ready to teach these techniques to a person with interest and a suitable background. The focus of the work will be on virus structures and their complexes with antibodies and receptors. Please send applications to: Michael Rossmann, Hanley Professor of Biological Sciences, Dept. of Biological Sciences, Tel: 765-494-4911, Purdue University, fax 765-496-1189, West Lafayette, IN 47907, e-mail: mgr@indiana.bio.purdue.edu, website http://www-structure.bio.purdue.edu/.

Postdoctoral Positions: Structural Studies of Proteins and Viruses Relevant to AIDS and Other Human Diseases
HIV Reverse Transcriptase: Structure Determination of Complexes with Substrates and Inhibitors and of Drug-Resistant Mutants; Structure-Based Drug Design/Viral Polymerases/Cellular Polymerases/Polymerase Mechanisms/Protein and Vaccine Engineering Using Combinatorial Mutagenesis. Highly motivated postdoctoral researchers are sought to participate in crystallographic structure determination and refinement of proteins and viruses, including HIV-1 reverse transcriptase with bound nucleic acids and drugs at high resolution (in collaboration with Stephen Hughes' laboratory at NCI-Frederick). Structures of HIV-1 RT complexed with a variety of nucleic acid template primers (DNA/DNA and RNA/DNA) and numerous inhibitors are under study, and we are pursuing structural and biochemical studies of drug-resistant mutants of HIV-1 RT to understand the obstacles these mutants pose to successful treatments. Another major project in the laboratory (co-directed by Dr. Gail Ferstandig Arnold) consists of vaccine engineering via combinatorial mutagenesis of human rhinoviruses to display immunogens from other pathogens. Crystals of human rhinovirus:HIV chimeras have been obtained and are being analyzed. A strong background in crystallography, chemistry, biochemistry, virology, or molecular biology is required. For the structure analysis projects, experience in macromolecular or synchrotron crystallography would be particularly helpful. State-of-the-art facilities are available in our laboratory at the Center for Advanced Biotechnology and Medicine (CABM) for crystallography, protein chemistry, molecular biology, virology, and molecular modeling. Send CV and names and addresses of three references to: Eddy Arnold, CABM and Rutgers University, 679 Hoes Lane, Piscataway, NJ, 08854-5638, Tel: 732-235-5323; fax 732-235-5788, E-mail: arnold@cabm.rutgers.edu, Lab website: http://www.cabm.rutgers.edu/~arnold.

Protein Crystallographers
Postdoctoral crystallographic research in the labs of Elizabeth Getzoff or John Tainer. Project topics include bacterial pili, superoxide dismutases and nitric oxide synthases in control of reactive oxygen species, protein photoreceptors and clocks, DNA-repair, metalloenzyme structure and design, and cell cycle. Minority applicants encouraged. Superb facilities and environment. For recent project details see http://www.scripps.edu/~edg/ and http://www.scripps.edu/~jat/. Send letter stating interests with c.v. and names of three references to Angela Walker, Molecular Biology MB4, The Scripps Research Institute, La Jolla, CA 92037. E-mail: alwalker@scripps.edu.

Positions Previously Listed
Postdoctoral Position - Electron Microscopic Study of Two Dimensional Crystals of Protein Kinase C . Several lattice forms of PKC-a and PKC-d are available for cryoelectron microscopy and other studies. Contact Robert Kretsinger (rhk5i@virginia.edu) Department of Biology, University of Virginia, Charlottessville, VA 22903 (804)982-5764 or Julie Sando (jjs@virginia.edu) Department of Pharmacology 924-5020 for further information.
Single Crystal X-ray Diffraction: Bruker AXS Inc, Madison, Wisconsin, industrial postdoctoral position. Contact: Sue Byram at 1-800-234-XRAY (1-608-276-3041) or sbyram@bruker-axs.com. Qualified applicants should send their resume tce to: Human Resources, Bruker Analytical X-ray Systems, 6300 Enterprise Lane, Madison, WI 53719-1173.